【药物名称】LY-180299
化学结构式(Chemical Structure):
参考文献No.34841
标题:Anti-viral method
作者:Colacino, J.M.; Hornback, W.J.; Mauldin, S.C.; Munroe, J.E.; Tang, J.C.-C. (Eli Lilly and Company)
来源:WO 9741849
合成路线图解说明:

The methylation of podocarpic acid (I) (J Org Chem 1974, 39: 1968) gives methyl O-methylpodocarpate (II), which is oxidized with CrO3 in acetic acid.

参考文献No.34952
标题:Anti-viral cpds.
作者:Hornback, W.J.; Munroe, J.E. (Eli Lilly and Company)
来源:EP 0806408; JP 2000510468; WO 9741822
合成路线图解说明:

The methylation of podocarpic acid (I) (J Org Chem 1974, 39: 1968) gives methyl O-methylpodocarpate (II), which is oxidized with CrO3 in acetic acid.

参考文献No.34954
标题:Anti-viral cpds.
作者:Hornback, W.J.; Mauldin, S.C.; Munroe, J.E. (Eli Lilly and Company)
来源:EP 0806411; JP 2000510464; WO 9742154
合成路线图解说明:

The methylation of podocarpic acid (I) (J Org Chem 1974, 39: 1968) gives methyl O-methylpodocarpate (II), which is oxidized with CrO3 in acetic acid.

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