4-ADMPP, ADD-213063-药物合成数据库

【药物名称】4-ADMPP, ADD-213063

化学结构式(Chemical Structure):

参考文献No.	560783
标题:	Anticonvulsant activity and interactions with neuronal voltage-dependent sodium channel of analogues of ameltolide
作者:	Vamecq, J.; Lambert, D.; Poupaert, J.H.; Masereel, B.; Stables, J.P.
来源:	J Med Chem 1998,41(18),3307

合成路线图解说明: Phthalimide (III) was prepared by condensation of 4-nitrophthalic anhydride (I) with 2,6-dimethylaniline (II) in refluxing AcOH. Reduction of the nitro group of (II) by transfer hydrogenation using cyclohexene and Pd/C provided the title aminophthalimide.