2-Butylbenzofuran (I) was acylated with 5-methoxythiophen-2-carbonyl chloride (II) in chloroform at 0 C to give the methanone compound (III). Ether cleavage of (III) was accomplished with borontribromide in chloroform to give the hydroxy compound (IV). Compound (IV) was treated with sodium methanolate and subsequently reacted with diethylaminoethylchloride in diethylcarbonate to give the alkylated product. This was treated with hydrochloric acid to yield crystaline E047/1. The final product was purified by two recrystallizations from an acetone/water mixture.