Risedronate sodium, NE-58095, Optinate Septimum, Benet, Optinate, Actonel-药物合成数据库

【药物名称】Risedronate sodium, NE-58095, Optinate Septimum, Benet, Optinate, Actonel

化学结构式(Chemical Structure):

参考文献No.	4763
标题:	Pharmaceutical compsns. containing geminal diphosphonates
作者:	Benedict, J.J.; Perkins, C.M. (The Procter & Gamble Co.)
来源:	AU 8551534; EP 0186405; ES 8707543; JP 1995285976; JP 1997202794; US 5583122

合成路线图解说明: Risedronic acid is prepared by treatment of 2-(3-pyridyl)acetic acid (I) with a mixture of phosphorous acid and phosphorus oxychloride at reflux for 2.5 h.

参考文献No.	213231
标题:	Risedronate Sodium
作者:	Mealy, N.; Casta馿r, J.; Prous, J.
来源:	Drugs Fut 1993,18(7),605

合成路线图解说明: Risedronic acid is prepared by treatment of 2-(3-pyridyl)acetic acid (I) with a mixture of phosphorous acid and phosphorus oxychloride at reflux for 2.5 h.