【药物名称】Balofloxacin dihydrate, Q-35, Baloxin, Neuroquinoron
化学结构式(Chemical Structure):
参考文献No.11543
标题:Novel quinolinecarboxylic acid derivatives
作者:Nagano, H.; Yokota, T.; Katoh, Y. (Chugai Seiyaku Co., Ltd.)
来源:EP 0342675; JP 91095177
合成路线图解说明:

By reaction of 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (I) with 3-(methylamino)piperidine (II) by means of triethylamine in refluxing acetonitrile.

参考文献No.173738
标题:Q-35
作者:Prous, J.; Casta馿r, J.
来源:Drugs Fut 1992,17(5),382
合成路线图解说明:

By reaction of 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (I) with 3-(methylamino)piperidine (II) by means of triethylamine in refluxing acetonitrile.

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