Sertaconazole nitrate, FI-7045(free base), Ertaczo, Ginedermofix, Zalain, Dermoseptic, Extens, Dermofix, Fisderm-药物合成数据库

【药物名称】Sertaconazole nitrate, FI-7045(free base), Ertaczo, Ginedermofix, Zalain, Dermoseptic, Extens, Dermofix, Fisderm

化学结构式(Chemical Structure):

参考文献No.	180857
标题:	Synthesis and antimycotic activity of (benzo[b]thienyl)methyl ethers of 1 -(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol and of (Z)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone oxime
作者:	Moreno-Ma馻s, M.; Raga, M.M.; Palac韓, C.; Ortiz, J.A.; Cuberes, M.R.; Castell? J.M.
来源:	Arzneim-Forsch Drug Res 1992,42(5a),691

合成路线图解说明: Sertaconazole nitrate has been synthesized by condensation of 1-(2,4-dichlorophenyl)-2-(1-imidazolyl)ethanol (I) with 3-(bromomethyl)-7-chlorobenzo[b]thiophene (II) by means of NaH in HMPT, followed by salification with HNO3.