2,6-Dimethylaniline (I) is converted to the diazonium salt (II), which is reduced with tin (II) chloride to the hydrazine (III). Reaction of (III) with N,N-dimethylcyanamide (IV) at 130 C gives B-GYKI-38233.

2,6-Dimethylaniline (I) is converted to the diazonium salt (II), which is reduced with tin (II) chloride to the hydrazine (III). Reaction of (III) with N,N-dimethylcyanamide (IV) at 130 C gives B-GYKI-38233.

A new synthesis for B-GYKI-38233 has been described: The reaction of cyanogen bromide (I) with dimethylamine (II) gives dimethylcyanamide (III), which is then condensed with 2,6-dimethylphenylhydrazine (IV) in anhydrous propanol at 110 C. Title compound was found to be an effective antiarrhythmic agent in animal models, with low toxicity.