Cilnidipine, Cinaldipine, FRC-8653, Cinalong, Atelec, Siscard-药物合成数据库

【药物名称】Cilnidipine, Cinaldipine, FRC-8653, Cinalong, Atelec, Siscard

化学结构式(Chemical Structure):

参考文献No.	1993
标题:	1,4-Dihydropyridine derivs., methods for their production and pharmaceutical compsns. comprising the same
作者:	Kutsuma, T.; Ikawa, H.; Sato, Y. (Otsuka Pharmaceutical Co., Ltd.)
来源:	EP 0161877; JP 1985233058; JP 1986007255; JP 1989025758; US 4672068

合成路线图解说明: By cyclization of 2-(3-nitrobenzylidene)acetocetic acid cinnamyl ester (I) with 2-aminocrotonic acid 2-methoxyethyl ester (II) by heating at 120 C.

参考文献No.	349968
标题:	Cinildipine
作者:	Mealy, N.; Casta馿r, J.
来源:	Drugs Fut 1996,21(3),249

合成路线图解说明: By cyclization of 2-(3-nitrobenzylidene)acetocetic acid cinnamyl ester (I) with 2-aminocrotonic acid 2-methoxyethyl ester (II) by heating at 120 C.