Technetium (99mTc) Teboroxime, CDO-MeB, TEBO, TcCl(CDO)3BMe, SQ-30217, CardioTec-药物合成数据库

【药物名称】Technetium (99mTc) Teboroxime, CDO-MeB, TEBO, TcCl(CDO)3BMe, SQ-30217, CardioTec

化学结构式(Chemical Structure):

参考文献No.	109022
标题:	Monocapped tris(dioxime) complexes of technetium(III): Synthesis and structural characterization of TcX(dioxime)3B-R (X = Cl, Br; dioxime = dimethylglyoxime, cyclohexanedione dioxime; R = CH3, C4H9)
作者:	Treher, E.N.; Francesconi, L.C.; Gougoutas, J.Z.; Malley, M.F.; Nunn, A.D.
来源:	Inorg Chem 1989,283411-6

合成路线图解说明: Tc-99m-teboroxime is prepared by the addition of 370-3700 MBq (10-100 mCi) of Tc-99m pertechnetate (obtained from a Mo-99/Tc-99m generator) to a lyophilized Cardiotec(R) kit, and then heating the kit at 100 C for 15 min. After cooling, Tc-99m-teboroxime is ready for patient administration. The radiochemical purity (RCP) of Tc-99m-teboroxime is consistently greater than 90%; this can be confirmed by paper chromatography. Tc-99m-teboroxime is stable in the kit for at least 6 h following its preparation. Teboroxime (both the Tc-99m and Tc-99 forms) is prepared by template synthesis as shown in the simplified reaction.

参考文献No.	147136
标题:	TECHNETIUM (99mTc) TEBOROXIME < Prop INN; USAN >
作者:	Jurisson, S.
来源:	Drugs Fut 1990,15(11),1085

合成路线图解说明: Tc-99m-teboroxime is prepared by the addition of 370-3700 MBq (10-100 mCi) of Tc-99m pertechnetate (obtained from a Mo-99/Tc-99m generator) to a lyophilized Cardiotec(R) kit, and then heating the kit at 100 C for 15 min. After cooling, Tc-99m-teboroxime is ready for patient administration. The radiochemical purity (RCP) of Tc-99m-teboroxime is consistently greater than 90%; this can be confirmed by paper chromatography. Tc-99m-teboroxime is stable in the kit for at least 6 h following its preparation. Teboroxime (both the Tc-99m and Tc-99 forms) is prepared by template synthesis as shown in the simplified reaction.