【药物名称】Miriplatin, SMP-11355, SM-11355, DACHPM, DACHPt(II)(Myr)2
化学结构式(Chemical Structure):
参考文献No.5045
标题:Liposoluble platinum (II) complex and preparation thereof
作者:Maeda, M.; Sasaki, T. (Sumitomo Pharmaceuticals Co., Ltd.)
来源:AU 8654358; EP 0193936; JP 1987000096
合成路线图解说明:

Dichlorocyclohexane-1,2-diamine platinum complex (II) was prepared from (R,R)-1,2-cyclohexanediamine (I) according to a known method. Subsequent treatment of (II) with aqueous silver nitrate produced the diaqua complex (III). Finally, displacement of H2O by means of sodium myristate (IV) gave rise to the title compound.

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