Actarit, MS-932, Mover, Orcl-药物合成数据库

【药物名称】Actarit, MS-932, Mover, Orcl

化学结构式(Chemical Structure):

参考文献No.	4957
标题:	Immunomodulating agents
作者:	Sato, S.; Tsurufuji, M.; Enomoto, H.; Sugiyama, M.; Shibata, Y.; Morita, I.; Munakata, H.; Kobayashi, M.; Wagatsuma, K. (Mitsubishi Chem. Inds. Co.; Ltd.)
来源:	DE 3317107; US 4720506

合成路线图解说明: The esterification of 4-aminophenylacetic acid (I) with ethanol - HCl in the usual way gives the ethyl ester (II), which is acylated with acetic anhydride in ethyl acetate yielding ethyl 4-acetaminophenylacetate (III). Finally, this compound is hydrolyzed with aqueous NaOH.

参考文献No.	103340
标题:	MS-932
作者:	Prous, J.; Casta馿r, J.
来源:	Drugs Fut 1989,14(8),759

合成路线图解说明: The esterification of 4-aminophenylacetic acid (I) with ethanol - HCl in the usual way gives the ethyl ester (II), which is acylated with acetic anhydride in ethyl acetate yielding ethyl 4-acetaminophenylacetate (III). Finally, this compound is hydrolyzed with aqueous NaOH.