【药物名称】DWA-2114
化学结构式(Chemical Structure):
参考文献No.61876
标题:DWA-2114
作者:Hoshi, A.
来源:Drugs Fut 1987,12(10),939
合成路线图解说明:

The reaction of 2 aminomethylpyrrolidine (I) with potassium tetrachloropiatinum (II) gives dichloro piatinum complex (III), which is nitrated with silver nitrate and followed by substitution with cyclobutanedicarboxylate (IV).

参考文献No.803936
标题:Synthesis and antitumor activity of platinum complexes (I)
作者:Morikawa, K.; Koizumi, M.; Endo, K.; Yono, T.; Mitusui, H.; Akamatsu, K.; Honda, H.
来源:106th Annu Meet Pharm Soc Jpn (Chiba) 1986,Abstr. 4E 10-2
合成路线图解说明:

The reaction of 2 aminomethylpyrrolidine (I) with potassium tetrachloropiatinum (II) gives dichloro piatinum complex (III), which is nitrated with silver nitrate and followed by substitution with cyclobutanedicarboxylate (IV).

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