【药物名称】L44
化学结构式(Chemical Structure):
参考文献No.53774
标题:L44/L44-O
作者:Quack, G.
来源:Drugs Fut 1987,12(4),349
合成路线图解说明:

L44-O is prepared by oxidizing L44 with 40% peracetic acid and the product is recristallized from ethanol.

合成路线图解说明:

L44 is prepared by alkylating p-cyclohexylphenol (I) with iosobutene using Aberlyst A 15 as a catalyst. The raw mixture (II) is esterified with nicotinoyl chloride hydrochloride (III). The product is purified by recristallization from ethanol.

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