BIOLF-70-药物合成数据库

【药物名称】BIOLF-70

化学结构式(Chemical Structure):

参考文献No.	50802
标题:	BIOLF-70
作者:	Ogilvie, K.K.; Gauntt, C.J.
来源:	Drugs Fut 1986,11(10),826

合成路线图解说明: By the condensation of 2-amino-6-chloropurine (I) (which has been silylated with 1,1,1,3,3,3-hexamethyldisilazane) with (1,3-dibenzyloxy-2-propoxy)methyl chloride (II) by means of mercuric cyanide in benzene at reflux. BIOLF-7O is purified by chromatography over silica gel.

参考文献No.	700114
标题:	Biologically active acylnucleoside analogues. II. The synthesis of 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine (BIOLF-62)
作者:	Smith, K.O.; Kennell, W.L.; Galloway, K.S.; Cheriyan, U.O.; Ogilvie, K.K.; Radatus, B.K.
来源:	Can J Chem 1982,603005

合成路线图解说明: By the condensation of 2-amino-6-chloropurine (I) (which has been silylated with 1,1,1,3,3,3-hexamethyldisilazane) with (1,3-dibenzyloxy-2-propoxy)methyl chloride (II) by means of mercuric cyanide in benzene at reflux. BIOLF-7O is purified by chromatography over silica gel.