| 异名/同义词 | BMS-986453 IS AN INVESTIGATIONAL DRUG PRODUCT CONTAINING CRYOPRESERVED CD3+CAR+ T CELLS THAT HAVE BEEN TRANSDUCED WITH A THIRD-GENERATION, REPLICATION-INCOMPETENT, SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR TO EXPRESS A DUAL TARGETING BCMA-SPECIFIC AND GPRC5D-SPECIFIC CHIMERIC ANTIGEN RECEPTOR (CAR) FOR INTRAVENOUS ADMINISTRATION. THE DUAL TARGETING CAR CONSISTS OF HUMAN ANTI-BCMA AND ANTI-GPRC5D SCFV BINDING DOMAINS, A MODIFIED HUMAN IGG4 HINGE, A CD28 TRANSMEMBRANE ANCHOR, AND THE 4-1BB AND CD3.ZETA. CHAIN SIGNALING DOMAINS
TUNLUCABTAGENE AUTOLEUCEL
TUNLUCABTAGENE AUTOLEUCEL [USAN]
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