U-4220

TREATMENT OF CF IN PATIENTS AGED 2 TO <6 YEARS OLD WHO HAVE IN THE CFTR GENE AT LEAST ONE F508DEL MUTATION OR A RESPONSIVE MUTATION BASED ON CLINICAL AND/OR IN VITRO DATA BY ADMINISTERING DAILY ELX/TEZ/IVA (100 MG/50 MG/75 MG) + IVA (75 MG)