| 商品名 | 申请号 | 产品号 | 申请类型 | 活性成分 | 剂型/给药途径 | 规格/剂量 | RLD | RS | 申请号原始批准/暂定批准日期 | 产品号批准日期 | 申请人 | 市场状态 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DIFFERIN | 020338 | 001 | NDA | ADAPALENE | SOLUTION;TOPICAL | 0.1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | Yes | No | 1996/05/31 | 1996/05/31 | GALDERMA LABS LP | Discontinued |
| DIFFERIN | 020380 | 002 | NDA | ADAPALENE | GEL;TOPICAL | 0.1% | Yes | Yes | 1996/05/31 | 2016/07/08 | GALDERMA LABS LP | Over-the-counter |
| DIFFERIN | 020748 | 001 | NDA | ADAPALENE | CREAM;TOPICAL | 0.1% | Yes | Yes | 2000/05/26 | 2000/05/26 | GALDERMA LABS LP | Prescription |
| DIFFERIN | 021753 | 001 | NDA | ADAPALENE | GEL;TOPICAL | 0.3% | Yes | Yes | 2007/06/19 | 2007/06/19 | GALDERMA LABS LP | Prescription |
| DIFFERIN | 022502 | 001 | NDA | ADAPALENE | LOTION;TOPICAL | 0.1% | Yes | Yes | 2010/03/17 | 2010/03/17 | GALDERMA LABS LP | Prescription |