欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Arsenic trioxide Mylan
适用类别Human
治疗领域Leukemia, Promyelocytic, Acute
通用名/非专利名称arsenic trioxide
活性成分arsenic trioxide
产品号EMEA/H/C/005235
患者安全信息No
许可状态Withdrawn
ATC编码L01XX27
是否额外监管No
是否仿制药或hybrid药物Yes
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2020/04/01
上市许可开发者/申请人/持有人Mylan Ireland Limited
人用药物治疗学分组Antineoplastic agents
兽用药物治疗学分组
审评意见日期2020/01/30
欧盟委员会决定日期2025/01/14
修订号6
治疗适应症Arsenic trioxide Mylan is indicated for induction of remission, and consolidation in adult patients with:- Newly diagnosed low to intermediate risk acute promyelocytic leukaemia (APL) (white blood cell count, ? 10 x 103/?l) in combination with all trans retinoic acid (ATRA)- Relapsed/refractory acute promyelocytic leukaemia (APL) (Previous treatment should have included a retinoid and chemotherapy)characterised by the presence of the t(15;17) translocation and/or the presence of the promyelocytic leukaemia/retinoic acid receptor alpha (PML/RAR alpha) gene. The response rate of other acute myelogenous leukaemia subtypes to arsenic trioxide has not beenexamined.
适用物种
兽用药物ATC编码
首次发布日期2020/04/17
最后更新日期2025/05/06
产品说明书https://www.ema.europa.eu/en/documents/product-information/arsenic-trioxide-mylan-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/arsenic-trioxide-mylan
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