欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Arsenic trioxide medac
适用类别Human
治疗领域Leukemia, Promyelocytic, Acute
通用名/非专利名称arsenic trioxide
活性成分arsenic trioxide
产品号EMEA/H/C/005218
患者安全信息No
许可状态Authorised
ATC编码L01XX27
是否额外监管No
是否仿制药或hybrid药物Yes
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2020/09/17
上市许可开发者/申请人/持有人medac Gesellschaft für klinische Spezialpräparate mbH
人用药物治疗学分组Antineoplastic agents
兽用药物治疗学分组
审评意见日期2020/07/23
欧盟委员会决定日期2022/04/22
修订号2
治疗适应症Arsenic trioxide medac is indicated for induction of remission, and consolidation in adult patients with: Newly diagnosed low-to-intermediate risk acute promyelocytic leukaemia (APL) (white blood cell count, ? 10 x 10³/?l) in combination with all-trans-retinoic acid (ATRA) Relapsed/refractory APL (previous treatment should have included a retinoid and chemotherapy) characterised by the presence of the t(15;17) translocation and/or the presence of the pro-myelocytic leukaemia/retinoic-acid-receptor-alpha (PML/RAR?) gene. The response rate of other acute myelogenous leukaemia subtypes to arsenic trioxide has not been examined.
适用物种
兽用药物ATC编码
首次发布日期2020/10/01
最后更新日期2022/04/26
产品说明书https://www.ema.europa.eu/en/documents/product-information/arsenic-trioxide-medac-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/arsenic-trioxide-medac
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