欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Nexpovio
适用类别Human
治疗领域Multiple Myeloma
通用名/非专利名称selinexor
活性成分selinexor
产品号EMEA/H/C/005127
患者安全信息No
许可状态Authorised
ATC编码L01XX66
是否额外监管Yes
是否仿制药或hybrid药物No
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2021/03/26
上市许可开发者/申请人/持有人Stemline Therapeutics B.V.
人用药物治疗学分组Antineoplastic agents
兽用药物治疗学分组
审评意见日期2021/01/28
欧盟委员会决定日期2023/08/14
修订号8
治疗适应症NEXPOVIO is indicated in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. in combination with dexamethasone for the treatment of multiple myeloma in adult patients who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, two immunomodulatory agents and an anti-CD38 monoclonal antibody, and who have demonstrated disease progression on the last therapy.
适用物种
兽用药物ATC编码
首次发布日期2021/05/27
最后更新日期2023/08/17
产品说明书https://www.ema.europa.eu/en/documents/product-information/nexpovio-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/nexpovio
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