欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Kevzara
适用类别Human
治疗领域Arthritis, Rheumatoid
通用名/非专利名称sarilumab
活性成分sarilumab
产品号EMEA/H/C/004254
患者安全信息No
许可状态Authorised
ATC编码L04AC14
是否额外监管Yes
是否仿制药或hybrid药物No
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2017/06/23
上市许可开发者/申请人/持有人Sanofi Winthrop Industrie
人用药物治疗学分组Immunosuppressants
兽用药物治疗学分组
审评意见日期2017/04/21
欧盟委员会决定日期2025/03/28
修订号15
治疗适应症Rheumatoid arthritisKevzara in combination with methotrexate (MTX) is indicated for the treatment of moderately to severely active rheumatoid arthritis (RA) in adult patients who have responded inadequately to, or who are intolerant to one or more disease modifying anti rheumatic drugs (DMARDs). Kevzara can be given as monotherapy in case of intolerance to MTX or when treatment with MTX is inappropriate. Polymyalgia rheumaticaKevzara is indicated for the treatment of polymyalgia rheumatica (PMR) in adult patients who have had an inadequate response to corticosteroids or who experience a relapse during corticosteroid taper. Polyarticular juvenile idiopathic arthritis Kevzara is indicated for the treatment of active polyarticular juvenile idiopathic arthritis (pJIA; rheumatoid factor positive or negative polyarthritis and extended oligoarthritis) in patients 2 years of age and older, who have responded inadequately to previous therapy with conventional synthetic DMARDs (csDMARDs). Kevzara may be used as monotherapy or in combination with MTX.
适用物种
兽用药物ATC编码
首次发布日期2017/08/24
最后更新日期2025/03/28
产品说明书https://www.ema.europa.eu/en/documents/product-information/kevzara-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/kevzara
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