欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Ciambra
适用类别Human
治疗领域Carcinoma, Non-Small-Cell Lung;Mesothelioma
通用名/非专利名称pemetrexed
活性成分pemetrexed disodium hemipentahydrate
产品号EMEA/H/C/003788
患者安全信息No
许可状态Withdrawn
ATC编码L01BA04
是否额外监管No
是否仿制药或hybrid药物Yes
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2015/12/02
上市许可开发者/申请人/持有人Menarini International Operations Luxembourg S.A.
人用药物治疗学分组Antineoplastic agents
兽用药物治疗学分组
审评意见日期2015/09/24
欧盟委员会决定日期2022/08/17
修订号7
治疗适应症Malignant pleural mesothelioma Ciambra in combination with cisplatin is indicated for the treatment of chemotherapy naïve patients with unresectable malignant pleural mesothelioma. Non-small cell lung cancer Ciambra in combination with cisplatin is indicated for the first line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology. Ciambra is indicated as monotherapy for the maintenance treatment of locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology in patients whose disease has not progressed immediately following platinum-based chemotherapy. Ciambra is indicated as monotherapy for the second line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology.
适用物种
兽用药物ATC编码
首次发布日期2018/08/03
最后更新日期2024/10/17
产品说明书https://www.ema.europa.eu/en/documents/product-information/ciambra-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/ciambra
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