欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Uptravi
适用类别Human
治疗领域Hypertension, Pulmonary
通用名/非专利名称selexipag
活性成分selexipag
产品号EMEA/H/C/003774
患者安全信息No
许可状态Authorised
ATC编码B01AC27
是否额外监管No
是否仿制药或hybrid药物No
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2016/05/12
上市许可开发者/申请人/持有人Janssen Cilag International NV
人用药物治疗学分组Antithrombotic agents
兽用药物治疗学分组
审评意见日期2016/01/28
欧盟委员会决定日期2024/11/08
修订号18
治疗适应症Uptravi is indicated for the long-term treatment of pulmonary arterial hypertension (PAH) in adult patients with WHO functional class (FC) II–III, either as combination therapy in patients insufficiently controlled with an endothelin receptor antagonist (ERA) and/or a phosphodiesterase type 5 (PDE-5) inhibitor, or as monotherapy in patients who are not candidates for these therapies. Efficacy has been shown in a PAH population including idiopathic and heritable PAH, PAH associated with connective tissue disorders, and PAH associated with corrected simple congenital heart disease.
适用物种
兽用药物ATC编码
首次发布日期2018/04/09
最后更新日期2025/05/22
产品说明书https://www.ema.europa.eu/en/documents/product-information/uptravi-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/uptravi
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