欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Xigduo
适用类别Human
治疗领域Diabetes Mellitus, Type 2
通用名/非专利名称dapagliflozin;metformin
活性成分metformin hydrochloride;dapagliflozin propanediol monohydrate
产品号EMEA/H/C/002672
患者安全信息No
许可状态Authorised
ATC编码A10BD15
是否额外监管No
是否仿制药或hybrid药物No
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2014/01/16
上市许可开发者/申请人/持有人AstraZeneca AB
人用药物治疗学分组Drugs used in diabetes;Combinations of oral blood glucose lowering drugs
兽用药物治疗学分组
审评意见日期2013/11/20
欧盟委员会决定日期2025/05/08
修订号25
治疗适应症Xigduo is indicated in adults for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise: •    in patients insufficiently controlled on their maximally tolerated dose of metformin alone  •    in combination with other medicinal products for the treatment of diabetes in patients insufficiently controlled with metformin and these medicinal products •    in patients already being treated with the combination of dapagliflozin and metformin as separate tablets. For study results with respect to combination of therapies, effects on glycaemic control and cardiovascular events, and the populations studied, see sections 4.4, 4.5 and 5.1.
适用物种
兽用药物ATC编码
首次发布日期2017/12/20
最后更新日期2025/12/18
产品说明书https://www.ema.europa.eu/en/documents/product-information/xigduo-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/xigduo
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