欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Xtandi
适用类别Human
治疗领域Prostatic Neoplasms
通用名/非专利名称enzalutamide
活性成分enzalutamide
产品号EMEA/H/C/002639
患者安全信息No
许可状态Authorised
ATC编码L02BB04
是否额外监管No
是否仿制药或hybrid药物No
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2013/06/21
拒绝上市许可日期2013/04/26
上市许可开发者/申请人/持有人Astellas Pharma Europe B.V.
人用药物治疗学分组Endocrine therapy
兽用药物治疗学分组
审评意见日期2013/04/25
欧盟委员会决定日期2025/07/31
修订号27
治疗适应症Xtandi is indicated for: as monotherapy or in combination with androgen deprivation therapy for the treatment of adult men with high risk biochemical recurrent (BCR) non-metastatic hormone sensitive prostate cancer (nmHSPC) who are unsuitable for salvage radiotherapy (see section 5.1). the treatment of adult men with metastatic hormone-sensitive prostate cancer (mHSPC) in combination with androgen deprivation therapy (see section 5.1). the treatment of adult men with high-risk non-metastatic castration-resistant prostate cancer (CRPC) (see section 5.1). the treatment of adult men with metastatic CRPC who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy in whom chemotherapy is not yet clinically indicated (see section 5.1). the treatment of adult men with metastatic CRPC whose disease has progressed on or after docetaxel therapy.
适用物种
兽用药物ATC编码
首次发布日期2018/02/08
最后更新日期2025/11/25
产品说明书https://www.ema.europa.eu/en/documents/product-information/xtandi-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/xtandi
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