欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Abseamed
适用类别Human
治疗领域Anemia;Kidney Failure, Chronic;Blood Transfusion, Autologous;Myelodysplastic Syndromes
通用名/非专利名称epoetin alfa
活性成分epoetin alfa
产品号EMEA/H/C/000727
患者安全信息No
许可状态Authorised
ATC编码B03XA01
是否额外监管No
是否仿制药或hybrid药物No
是否生物类似药Yes
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2007/08/27
拒绝上市许可日期2009/06/18
上市许可开发者/申请人/持有人Medice Arzneimittel Pütter GmbH Co. KG
人用药物治疗学分组Antianemic preparations
兽用药物治疗学分组
欧盟委员会决定日期2025/07/11
修订号26
治疗适应症Treatment of symptomatic anaemia associated with chronic renal failure (CRF) in adult and paediatric patients: treatment of anaemia associated with chronic renal failure in paediatric and adult patients on haemodialysis and adult patients on peritoneal dialysis; treatment of severe anaemia of renal origin accompanied by clinical symptoms in adult patients with renal insufficiency not yet undergoing dialysis. Treatment of anaemia and reduction of transfusion requirements in adult patients receiving chemotherapy for solid tumours, malignant lymphoma or multiple myeloma, and at risk of transfusion as assessed by the patient's general status (e.g. cardiovascular status, pre existing anaemia at the start of chemotherapy). Abseamed can be used to increase the yield of autologous blood from patients in a predonation programme. Its use in this indication must be balanced against the reported risk of thromboembolic events. Treatment should only be given to patients with moderate anaemia (haemoglobin (Hb) 10-13 g/dl [6.2-8.1 mmol/l], no iron deficiency), if blood saving procedures are not available or insufficient when the scheduled major elective surgery requires a large volume of blood (4 or more units of blood for females or 5 or more units for males). Abseamed can be used to reduce exposure to allogeneic blood transfusions in adult non iron deficient patients prior to major elective orthopaedic surgery, having a high perceived risk for transfusion complications. Use should be restricted to patients with moderate anaemia (e.g. Hb 10-13 g/dl) who do not have an autologous predonation programme available and with an expected blood loss of 900 to 1800 ml.
适用物种
兽用药物ATC编码
首次发布日期2016/11/14
最后更新日期2025/07/11
产品说明书https://www.ema.europa.eu/en/documents/product-information/abseamed-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/abseamed
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