欧盟EMA药品数据库(European Medicines Agency Authorisation of Medicines DataBase)
商品名称Rapamune
适用类别Human
治疗领域Graft Rejection;Kidney Transplantation
通用名/非专利名称sirolimus
活性成分sirolimus
产品号EMEA/H/C/000273
患者安全信息No
许可状态Authorised
ATC编码L04AH01
是否额外监管No
是否仿制药或hybrid药物No
是否生物类似药No
是否附条件批准No
是否特殊情形No
是否加速审评No
是否罕用药No
上市许可日期2001/03/13
上市许可开发者/申请人/持有人Pfizer Europe MA EEIG
人用药物治疗学分组Immunosuppressants
兽用药物治疗学分组
审评意见日期2000/11/16
欧盟委员会决定日期2025/09/11
修订号49
治疗适应症Rapamune is indicated for the prophylaxis of organ rejection in adult patients at low to moderate immunological risk receiving a renal transplant. It is recommended that Rapamune be used initially in combination with ciclosporin microemulsion and corticosteroids for 2 to 3 months. Rapamune may be continued as maintenance therapy with corticosteroids only if ciclosporin microemulsion can be progressively discontinued. Rapamune is indicated for the treatment of patients with sporadic lymphangioleiomyomatosis with moderate lung disease or declining lung function.
适用物种
兽用药物ATC编码
首次发布日期2018/08/02
最后更新日期2025/09/17
产品说明书https://www.ema.europa.eu/en/documents/product-information/rapamune-epar-product-information_en.pdf
公共评估报告https://www.ema.europa.eu/en/medicines/human/EPAR/rapamune
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