Title: Dydrogesterone
CAS Registry Number: 152-62-5
CAS Name: (9b,10a)-Pregna-4,6-diene-3,20-dione
Additional Names: 10a-pregna-4,6-diene-3,20-dione; 6-dehydro-retro-progesterone; 10a-isopregnenone
Trademarks: Dufaston (ISM); Duphaston (Roxane); Gynorest (Mead Johnson); Prodel; Retrone
Molecular Formula: C21H28O2
Molecular Weight: 312.45
Percent Composition: C 80.72%, H 9.03%, O 10.24%
Literature References: Prepn: Westerhof, Reerink, Rec. Trav. Chim. 79, 771 (1960); Rappoldt, Westerhof, ibid. 80, 43 (1961).
Properties: Crystals from acetone + hexane, mp 169-170°. [a]D25 -484.5° (chloroform). uv max: 286.5 nm (e 26400).
Melting point: mp 169-170°
Optical Rotation: [a]D25 -484.5° (chloroform)
Absorption maximum: uv max: 286.5 nm (e 26400)
Therap-Cat: Progestogen.
Keywords: Progestogen. |