Structural Formula Vector Image
Title: Budipine
CAS Registry Number: 57982-78-2
CAS Name: 1-(1,1-Dimethylethyl)-4,4-diphenylpiperidine
Additional Names: 1-tert-butyl-4,4-diphenylpiperidine
Molecular Formula: C21H27N
Molecular Weight: 293.45
Percent Composition: C 85.95%, H 9.27%, N 4.77%
Literature References: Centrally acting deriv of diphenylpiperidine. Prepn: H. G. Menge, J. Klosa, DE 1936452; eidem, US 4016280 (1969, 1977 both to Byk Gulden). Pharmacological studies: U. Brand, H. G. Menge, Arzneim.-Forsch. 30, 1242 (1980); M. Eltze, ibid. 1129; H. G. Menge, U. Brand, ibid. 32, 85 (1982). Comparison to other drugs in treatment of dyskinesias: J. Siegfried, Can. J. Neurol. Sci. 6, 89 (1979). Clinical evaluation with levodopa in Parkinson's disease: K. Jellinger, H. Bliesath, J. Neurol. 234, 280 (1987).
Derivative Type: Hydrochloride
CAS Registry Number: 63661-61-0
Trademarks: Parkinsan (Byk Gulden)
Molecular Formula: C21H27N.HCl
Molecular Weight: 329.91
Percent Composition: C 76.45%, H 8.55%, N 4.25%, Cl 10.75%
Properties: LD50 in male mice, rats (mg/kg): 120, 165 orally; 33, 28 i.v. (Menge, Brand).
Toxicity data: LD50 in male mice, rats (mg/kg): 120, 165 orally; 33, 28 i.v. (Menge, Brand)
Therap-Cat: Antiparkinsonian.
Keywords: Antiparkinsonian.

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