Structural Formula Vector Image
Title: Xipamide
CAS Registry Number: 14293-44-8
CAS Name: 4-Chloro-5-sulfamoyl-2¢,6¢-salicyloxylidide
Additional Names: 4-chloro-2¢,6¢-dimethyl-5-sulfamoylsalicylanilide; 4-chloro-5-sulfamylsalicyloyl-2¢,6¢-dimethylanilide
Manufacturers' Codes: Bei-1293
Trademarks: Aquaphor (Lilly); Chronexan (Viatris); Diurexan (Viatris); Lumitens (Solvay)
Molecular Formula: C15H15ClN2O4S
Molecular Weight: 354.81
Percent Composition: C 50.78%, H 4.26%, Cl 9.99%, N 7.90%, O 18.04%, S 9.04%
Literature References: Salicylic acid derivative. Prepn: NL 6607680; Liebenow, US 3567777 (1966, 1970 both to P. Beiersdorf). Clinical studies: O. Hammer, U. Dembowski, Med. Klin. 64, 1862 (1969); R. Fischer, A. Lenhartz, Med. Welt 1970, 270. Review of pharmacology and therapeutic efficacy: B. N. C. Prichard, R. N. Brogden, Drugs 30, 313-332 (1985).
Properties: Crystals from methanol-water, mp 256°.
Melting point: mp 256°
Therap-Cat: Diuretic; antihypertensive.
Keywords: Antihypertensive; Sulfonamide Derivatives; Diuretic; Sulfonamide Derivatives.

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