Tyropanoate Sodium
Structural Formula Vector Image
Title: Tyropanoate Sodium
CAS Registry Number: 7246-21-1
CAS Name: a-Ethyl-2,4,6-triiodo-3-[(1-oxobutyl)amino]benzenepropanoic acid monosodium salt
Additional Names: 3-butyramido-a-ethyl-2,4,6-triiodohydrocinnamic acid sodium salt; a-ethyl-b-(2,4,6-triiodo-3-butyramidophenyl)propionic acid sodium salt; sodium tyropanoate
Manufacturers' Codes: Win-8851-2
Trademarks: Bilopaque (Sterling Winthrop); Lumopaque (Winthrop); Tyropaque (Torii)
Molecular Formula: C15H17I3NNaO3
Molecular Weight: 663.00
Percent Composition: C 27.17%, H 2.58%, I 57.42%, N 2.11%, Na 3.47%, O 7.24%
Literature References: Prepn: S. Archer, J. O. Hoppe, US 2895988 (1959 to Sterling Drug); and pharmacology: J. O. Hoppe et al., J. Med. Chem. 13, 997 (1970). Clinical trials: S. Y. Han, D. M. Witten, Radiology 112, 529 (1974); R. F. Thoeni, A. A. Moss, ibid. 144, 271 (1982).
Properties: Colorless solid from ethyl ether, mp 208-210°. Soluble in water. LD50 i.v. in mice: 720 mg/kg (Hoppe).
Melting point: mp 208-210°
Toxicity data: LD50 i.v. in mice: 720 mg/kg (Hoppe)
Derivative Type: Free acid
Molecular Formula: C15H18I3NO3
Molecular Weight: 641.02
Percent Composition: C 28.11%, H 2.83%, I 59.39%, N 2.19%, O 7.49%
Properties: Crystals from ethyl oxyacetate, mp 182-184°.
Melting point: mp 182-184°
Therap-Cat: Diagnostic aid (radiopaque medium¾cholecystographic).
Keywords: Diagnostic Aid (Radiopaque Medium).

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