Trilobine
Structural Formula Vector Image
Title: Trilobine
CAS Registry Number: 6138-73-4
CAS Name: (1¢a)-6¢,7-Epoxy-6,12¢-dimethoxy-2¢-methyloxyacanthan
Molecular Formula: C35H34N2O5
Molecular Weight: 562.65
Percent Composition: C 74.71%, H 6.09%, N 4.98%, O 14.22%
Literature References: From root of Cocculus trilobus DC. and C. sarmentosus Diels, Menispermaceae: Tomita et al., J. Pharm. Soc. Jpn. 48, 83 (1928); 50, 127 (1930); 62, 468, 481 (1942). Structure: Kondo, Tomita, Ann. 497, 104 (1932); Inubushi, Nomura, Tetrahedron Lett. 1962, 1133. Total synthesis of trilobine and isotrilobine: Y. Inubushi et al., Chem. Pharm. Bull. 25, 1636 (1977).
Properties: Crystals from benzene, mp 237°. [a]D +307° (chloroform). Practically insol in water. Sparingly sol in alcohol, acetone, ether. Sol in chloroform.
Melting point: mp 237°
Optical Rotation: [a]D +307° (chloroform)
 
Derivative Type: Isotrilobine
CAS Registry Number: 26195-62-0
Additional Names: Homotrilobine; N-methyltrilobine
Molecular Formula: C36H36N2O5
Molecular Weight: 576.68
Percent Composition: C 74.98%, H 6.29%, N 4.86%, O 13.87%
Properties: Crystals from acetone, mp 215°. [a]D +317° (chloroform).
Melting point: mp 215°
Optical Rotation: [a]D +317° (chloroform)

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