Structural Formula Vector Image
Title: Thiamiprine
CAS Registry Number: 5581-52-2
CAS Name: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purin-2-amine
Additional Names: 2-amino-6-[(1-methyl-4-nitroimidazol-5-yl)thio]purine; 2-amino-6-(1¢-methyl-4¢-nitro-5¢-imidazolyl)mercaptopurine
Trademarks: Guaneran (Burroughs Wellcome)
Molecular Formula: C9H8N8O2S
Molecular Weight: 292.28
Percent Composition: C 36.98%, H 2.76%, N 38.34%, O 10.95%, S 10.97%
Literature References: Prepd from thioguanine and 1-methyl-4-nitro-5-chloroimidazole: Hitchings, Elion, US 3056785 (1962 to Burroughs Wellcome).
Properties: Crystals, dec slowly >200°. uv max: 320 nm at pH 1; 315 nm at pH 11.
Absorption maximum: uv max: 320 nm at pH 1; 315 nm at pH 11
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Purine Analogs.

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