Structural Formula Vector Image
Title: Thenyldiamine
CAS Registry Number: 91-79-2
CAS Name: N,N-Dimethyl-N¢-2-pyridinyl-N¢-(3-thienylmethyl)-1,2-ethanediamine
Additional Names: 2-[(2-dimethylaminoethyl)-3-thenylamino]pyridine; N,N-dimethyl-N¢-(a-pyridyl)-N¢-(3-methylthienyl)ethylenediamine; N-(a-pyridyl)-N-(b-thenyl)-N¢,N¢-dimethylethylenediamine; N-(2-dimethylaminoethyl)-N-2-pyridyl-3-thenylamine; dethylandiamine
Manufacturers' Codes: Win-2848
Trademarks: Thenfadil (Winthrop)
Molecular Formula: C14H19N3S
Molecular Weight: 261.39
Percent Composition: C 64.33%, H 7.33%, N 16.08%, S 12.27%
Literature References: Prepn: Campaigne, LeSuer, J. Am. Chem. Soc. 71, 333 (1949). Toxicity study: Hoppe, Lands, J. Pharmacol. Exp. Ther. 97, 371 (1949).
Properties: Free base, liquid. bp1.0 169-172°. nD20 1.5915.
Boiling point: bp1.0 169-172°
Index of refraction: nD20 1.5915
Derivative Type: Hydrochloride
Molecular Formula: C14H19N3S.HCl
Molecular Weight: 297.85
Percent Composition: C 56.45%, H 6.77%, N 14.11%, S 10.77%, Cl 11.90%
Properties: Crystals from methanol, mp 169.5-170°. Bitter taste. Sol in water up to 20%. Slightly sol in alc. pH of 1% aq soln 6.5. LD50 orally in rats: 525 mg/kg (Hoppe, Lands).
Melting point: mp 169.5-170°
Toxicity data: LD50 orally in rats: 525 mg/kg (Hoppe, Lands)
Therap-Cat: Hydrochloride as antihistaminic.
Keywords: Antihistaminic; Ethylenediamine Derivatives.

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