Talastine
Structural Formula Vector Image
Title: Talastine
CAS Registry Number: 16188-61-7
CAS Name: 2-[2-(Dimethylamino)ethyl]-4-(phenylmethyl)-1(2H)-phthalazinone
Additional Names: 4-benzyl-2-[2-(dimethylamino)ethyl]-1(2H)-phthalazinone
Molecular Formula: C19H21N3O
Molecular Weight: 307.39
Percent Composition: C 74.24%, H 6.89%, N 13.67%, O 5.20%
Literature References: Prepn: Engelbrecht et al., DE 1046625; eidem, US 3017411 (1958, 1962, both to VEB Deutsches Hydrierwerk Rodleben). Pharmacology: D. Lenke, Arzneim.-Forsch. 7, 678 (1957).
Properties: Liquid, bp0.3 215-222°.
Boiling point: bp0.3 215-222°
 
Derivative Type: Hydrochloride
CAS Registry Number: 16188-76-4
Manufacturers' Codes: HL-2186
Trademarks: Ahanon (Rodleben)
Molecular Formula: C19H21N3O.HCl
Molecular Weight: 343.85
Percent Composition: C 66.37%, H 6.45%, N 12.22%, O 4.65%, Cl 10.31%
Properties: Crystals, mp 178°. LD50 i.p. in mice: 116 mg/kg (Lenke).
Melting point: mp 178°
Toxicity data: LD50 i.p. in mice: 116 mg/kg (Lenke)
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Ethylenediamine Derivatives.

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