Rimiterol
Structural Formula Vector Image
Title: Rimiterol
CAS Registry Number: 32953-89-2
CAS Name: 4-(Hydroxy-2-piperidinylmethyl)-1,2-benzenediol
Additional Names: erythro-a-(3,4-dihydroxyphenyl)-2-piperidinemethanol; erythro-3,4-dihydroxyphenyl-2-piperidinylcarbinol
Molecular Formula: C12H17NO3
Molecular Weight: 223.27
Percent Composition: C 64.55%, H 7.67%, N 6.27%, O 21.50%
Literature References: Prepn: G. H. Sankey, K. D. E. Whiting, DE 2024049; idem, US 3910934 (1970, 1975 to 3M); C. Kaiser, S. T. Ross, DE 2047937; idem, US 3705169 (1971, 1972 to SK & F); G. H. Sankey, K. D. E. Whiting, J. Heterocycl. Chem. 9, 1049 (1972). Pharmacology: Carney et al., Arch. Int. Pharmacodyn. Ther. 194, 334 (1971); Griffin, Turner, J. Clin. Pharmacol. 11, 280 (1971); Bowman, Rodger, Br. J. Pharmacol. 45, 574 (1972).
Properties: Crystals from ethyl acetate, mp 203-204°.
Melting point: mp 203-204°
 
Derivative Type: Hydrobromide
CAS Registry Number: 31842-61-2
Manufacturers' Codes: R-798; WG-253
Trademarks: Asmaten (3M Pharma); Pulmadil (3M Pharma)
Molecular Formula: C12H17NO3.HBr
Molecular Weight: 304.18
Percent Composition: C 47.38%, H 5.96%, N 4.60%, O 15.78%, Br 26.27%
Properties: White powder, mp 220° (dec).
Melting point: mp 220° (dec)
 
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.

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