Revaprazan
Structural Formula Vector Image
Title: Revaprazan
CAS Registry Number: 199463-33-7
CAS Name: 4-(3,4-Dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-2-pyrimidinamine
Additional Names: 5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine
Molecular Formula: C22H23FN4
Molecular Weight: 362.44
Percent Composition: C 72.90%, H 6.40%, F 5.24%, N 15.46%
Literature References: Gastric proton pump inhibitor. Prepn: J. W. Lee et al., WO 9605177; eidem, US 5750531 (1996, 1998 both to Yuhan). HPLC determn in plasma and urine: K. S. Han et al., J. Chromatogr. B 696, 312 (1997). Clinical pharmacokinetics: K.-S. Yu et al., J. Clin. Pharmacol. 44, 73 (2004).
 
Derivative Type: Hydrochloride
CAS Registry Number: 178307-42-1
Manufacturers' Codes: YH-1885
Trademarks: Revanex (Yuhan)
Molecular Formula: C22H23FN4.HCl
Molecular Weight: 398.90
Percent Composition: C 66.24%, H 6.06%, F 4.76%, N 14.05%, Cl 8.89%
Properties: mp 205-208°.
Melting point: mp 205-208°
 
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative.

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