Structural Formula Vector Image
Title: Pridinol
CAS Registry Number: 511-45-5
CAS Name: a,a-Diphenyl-1-piperidinepropanol
Additional Names: 1,1-diphenyl-3-piperidino-1-propanol; 3-piperidino-1,1-diphenyl-1-propanol; 1,1-diphenyl-3-(1-piperidyl)-1-propanol; 3-(N-piperidyl)-1,1-diphenyl-1-propanol; ridinol
Manufacturers' Codes: C-238
Molecular Formula: C20H25NO
Molecular Weight: 295.42
Percent Composition: C 81.31%, H 8.53%, N 4.74%, O 5.42%
Literature References: May be prepd from ethyl 1-piperidinepropionate and phenylmagnesium bromide: Adamson, GB 624118 (1949 to Wellcome Found.). Toxicity study: R. W. Cunningham et al., J. Pharmacol. Exp. Ther. 96, 151 (1949).
Properties: Crystals, mp 120-121°. Soluble in acetone.
Melting point: mp 120-121°
Derivative Type: Hydrochloride
CAS Registry Number: 968-58-1
Trademarks: Parks 12 (Novartis)
Molecular Formula: C20H25NO.HCl
Molecular Weight: 331.88
Percent Composition: C 72.38%, H 7.90%, N 4.22%, O 4.82%, Cl 10.68%
Properties: Crystals, dec 238°. Sol in alc. LD50 in mice, rats (mg/kg): 35, 33 i.v.; 131, 91 i.p. (Cunningham).
Toxicity data: LD50 in mice, rats (mg/kg): 35, 33 i.v.; 131, 91 i.p. (Cunningham)
Derivative Type: Methanesulfonate
CAS Registry Number: 6856-31-1
Additional Names: Pridinol mesylate
Trademarks: Konlax (Nippon Shinyaku); Loxeen (Tobishi); Lyseen (Novartis); Myoson (Strathmann)
Molecular Formula: C20H25NO.CH3SO3H
Molecular Weight: 391.52
Percent Composition: C 64.42%, H 7.47%, N 3.58%, O 16.35%, S 8.19%
Properties: Crystals, mp 152.5-155.0°. Sparingly sol in water.
Melting point: mp 152.5-155.0°
Therap-Cat: Antiparkinsonian; muscle relaxant (skeletal).

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