Pipazethate
Structural Formula Vector Image
Title: Pipazethate
CAS Registry Number: 2167-85-3
CAS Name: 10H-Pyrido[3,2-b][1,4]benzothiadiazine-10-carboxylic acid 2-(2-piperidinoethoxy)ethyl ester
Additional Names: 2-(2-piperidinoethoxy)ethyl 10H-pyrido[3,2-b][1,4]benzothiadiazine-10-carboxylate; thiophenylpyridylamino-10-carboxylic acid piperidinoethoxyethyl ester; 2-(2-piperidinoethoxy)ethyl 10-thia-1,9-diazaanthracene-10-carboxylate; 1-azaphenothiazine-10-carboxylic acid 2-(2-piperidinoethoxy)ethyl ester
Manufacturers' Codes: D-254
Molecular Formula: C21H25N3O3S
Molecular Weight: 399.51
Percent Composition: C 63.13%, H 6.31%, N 10.52%, O 12.01%, S 8.03%
Literature References: Prepn: Schuler et al., Ann. 673, 102 (1964); Schuler, US 2989529 (1961 to Degussa).
 
Derivative Type: Hydrochloride
CAS Registry Number: 6056-11-7
Trademarks: Lenopect (Draco); Selvigon (ICN-Galenika); Selvjgon (Rorer); Theratuss (Squibb)
Molecular Formula: C21H25N3O3S.HCl
Molecular Weight: 435.97
Percent Composition: C 57.85%, H 6.01%, N 9.64%, O 11.01%, S 7.35%, Cl 8.13%
Properties: Pale yellow crystals from isopropanol, mp 160-161°. Soluble in water, methanol. Practically insol in acetone, petr ether. LD50 orally in rats: 560 mg/kg (Schuler).
Melting point: mp 160-161°
Toxicity data: LD50 orally in rats: 560 mg/kg (Schuler)
 
Therap-Cat: Antitussive.
Keywords: Antitussive.

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