Structural Formula Vector Image
Title: Phosphamidon
CAS Registry Number: 13171-21-6
CAS Name: Phosphoric acid 2-chloro-3-(diethylamino)-1-methyl-3-oxo-1-propenyl dimethyl ester
Additional Names: phosphoric acid dimethyl ester, ester with 2-chloro-N,N-diethyl-3-hydroxycrotonamide; 2-chloro-2-diethylcarbamoyl-1-methylvinyl dimethyl phosphate
Manufacturers' Codes: Ciba 570; ENT-25515
Trademarks: Kinadon (United Phosphorus)
Molecular Formula: C10H19ClNO5P
Molecular Weight: 299.69
Percent Composition: C 40.08%, H 6.39%, Cl 11.83%, N 4.67%, O 26.69%, P 10.34%
Literature References: Cholinesterase inhibitor. Commercial product consists of 73/27 mixture of cis (Z)/ trans (E) isomers. Prepn: Beriger, Sallmann, US 2908605 (1959 to Ciba); Anliker et al., Helv. Chim. Acta 44, 1622 (1961). GC determn: W. E. Westlake et al., J. Agric. Food Chem. 21, 846 (1973). Toxicity data: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969). Review: Residue Rev. 37, 1-202 (1971).
Properties: Oil. d425 1.2132. nD25 1.4718. bp1.5 162°; bp0.001 120°. mp -45°. Vapor pressure at 20°: 2.5 ´ 10-5 mm Hg. Misc with water and most organic solvents except saturated hydrocarbons. One gram dissolves in ~30 g hexane. Stable in neutral or acid media; hydrolyzed by alkali. LD50 orally in rats: 24 mg/kg (Gaines).
Melting point: mp -45°
Boiling point: bp1.5 162°; bp0.001 120°
Index of refraction: nD25 1.4718
Density: d425 1.2132
Toxicity data: LD50 orally in rats: 24 mg/kg (Gaines)
CAUTION: See Parathion.
Use: Insecticide.

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