Structural Formula Vector Image
Title: Pentylenetetrazole
CAS Registry Number: 54-95-5
CAS Name: 6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine
Additional Names: a,b-cyclopentamethylenetetrazole; 1,5-pentamethylenetetrazole; 6,7,8,9-tetrahydro-5-azepotetrazole; 1,2,3,3a-tetrazacyclohepta-8a,2-cyclopentadiene; 7,8,9,10-tetrazabicyclo[5.3.0]-8,10-decadiene; pentetrazol
Trademarks: Cardiazol (Knoll); Cenalene-M (Central Pharm.); Cenazol; Coranormol; Corazole; Corvasol (Rieswerke); Deumacard (Jenapharm); Gewazol; Korazol; Metrazol (Knoll); Phrenazol; Ventrazol
Molecular Formula: C6H10N4
Molecular Weight: 138.17
Percent Composition: C 52.16%, H 7.29%, N 40.55%
Literature References: Prepd by the addition of cyclohexanone to a benzene or Tetralin soln of hydrazoic acid: Schmidt, Ber. 57, 704 (1924); US 1564631 (1925); US 1599493 (1926); Prochazka, CS 92456 (1959), C.A. 56, 4776e (1962). Synthesis from caprolactam: Glushkov, Golovchinskaya, Zh. Prikl. Khim. 32, 920 (1959); Med. Prom. SSSR 14, no. 1, 12 (1960). Toxicity study: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Slightly pungent, bitter crystals, mp 57-60°. Freely sol in water, most organic solvents. Aq solns are neutral to litmus. Very stable, not easily attacked by other substances. LD50 in rats (mg/kg): 85±2 s.c., 62 i.p. (Goldenthal).
Melting point: mp 57-60°
Toxicity data: LD50 in rats (mg/kg): 85±2 s.c., 62 i.p. (Goldenthal)
Therap-Cat: CNS stimulant.
Therap-Cat-Vet: CNS stimulant; narcotic antagonist.
Keywords: CNS Stimulant.

Other Monographs:
TESNidulinMagenta IUranium Peroxide
TuftsinCarbon NitrideCadmium Oxideα-Tocotrienol
Methyl Ethyl KetoneDeoxyepinephrineDihydroactinidiolideCytolipin H
PentapiperideLead SulfideIloperidoneSelenium Oxide
©2006-2023 DrugFuture->Chemical Index Database