Structural Formula Vector Image
Title: Oxolamine
CAS Registry Number: 959-14-8
CAS Name: N,N-Diethyl-3-phenyl-1,2,4-oxadiazole-5-ethanamine
Additional Names: 5-(2-diethylaminoethyl)-3-phenyl-1,2,4-oxadiazole; 3-phenyl-5-(b-diethylaminoethyl)-1,2,4-oxadiazole
Manufacturers' Codes: 683-M
Molecular Formula: C14H19N3O
Molecular Weight: 245.32
Percent Composition: C 68.54%, H 7.81%, N 17.13%, O 6.52%
Literature References: Prepn: DE 1097998 (1961 to Angelini Francesco), C.A. 56, 11598h (1962). Teratogenicity studies of oxolamine citrate: L. Nilsson, Arzneim.-Forsch. 17, 781 (1967).
Properties: Liquid, bp0.4 127°.
Boiling point: bp0.4 127°
Derivative Type: Hydrochloride
CAS Registry Number: 1219-20-1
Molecular Formula: C14H19N3O.HCl
Molecular Weight: 281.78
Percent Composition: C 59.67%, H 7.15%, N 14.91%, O 5.68%, Cl 12.58%
Properties: Crystals, mp 153-154°.
Melting point: mp 153-154°
Derivative Type: Citrate
CAS Registry Number: 1949-20-8
Manufacturers' Codes: AF-438
Trademarks: Bredon (Organon); Broncatar (Pulitzer); Perebron (Angelini); Prilon (Cassenne); Flogobron (Intersint); Oxarmin
Molecular Formula: C14H19N3O.C6H8O7
Molecular Weight: 437.44
Percent Composition: C 54.91%, H 6.22%, N 9.61%, O 29.26%
Properties: Crystals, slightly sol in water, alcohol. uv max (aq soln): 239 nm (e 260), 273, 283 nm.
Absorption maximum: uv max (aq soln): 239 nm (e 260), 273, 283 nm
Therap-Cat: In inflammatory conditions of respiratory tract.
Keywords: Antitussive.

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