Structural Formula Vector Image
Title: Mebhydroline
CAS Registry Number: 524-81-2
CAS Name: 2,3,4,5-Tetrahydro-2-methyl-5-(phenylmethyl)-1H-pyrido[4,3-b]indole
Additional Names: 5-benzyl-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indole; 3-methyl-9-benzyl-1,2,3,4-tetrahydro-g-carboline; 5-benzyl-1,2,3,4-tetrahydro-2-methyl-g-carboline; N-methyl-9-benzyltetrahydro-g-carboline
Trademarks: Incidal
Molecular Formula: C19H20N2
Molecular Weight: 276.38
Percent Composition: C 82.57%, H 7.29%, N 10.14%
Literature References: Prepn: Hörlein, Ber. 87, 463 (1954); GB 721171 (1954 to Bayer); Hörlein, US 2786059 (1957 to Schenley). Pharmacology of Diazoline: Kharkevich, Farmakol. Toksikol. 20(no. 6), 46 (1957).
Properties: Minute crystals, mp 95°. bp1 207-215°. Practically insol in water. Freely sol in methanol, ethanol, acetone, chloroform. Slightly sol in ether.
Melting point: mp 95°
Boiling point: bp1 207-215°
Derivative Type: 1,5-Naphthalenedisulfonate salt
CAS Registry Number: 6153-33-9
Trademarks: Diazoline; Fabahistin (Bayer); Omeril (Bayer)
Molecular Formula: (C19H20N2)2.C10H8O6S2
Molecular Weight: 841.05
Percent Composition: C 68.55%, H 5.75%, N 6.66%, O 11.41%, S 7.62%
Properties: White powder, dec 280°. Practically insol in water. Sparingly sol in hot glacial acetic acid. Sol in hot formamide, giving a yellow soln.
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic.

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