Lysine Acetylsalicylate
Structural Formula Vector Image
Title: Lysine Acetylsalicylate
CAS Registry Number: 62952-06-1
CAS Name: DL-Lysine mono[2-(acetyloxy)benzoate]
Additional Names: lysine monosalicylate acetate; aspirin lysine salt; LAS
Trademarks: Aspidol (Piam); Aspisol (Bayer); Delgesic (Karlspharma); Flectadol (Maggioni); Lysal (Gellini); Quinvet (Neopharmed); Venopirin (Green Cross); Vetalgina (ICC)
Molecular Formula: C15H22N2O6
Molecular Weight: 326.34
Percent Composition: C 55.21%, H 6.79%, N 8.58%, O 29.42%
Literature References: Water soluble, injectable aspirin derivative. Prepn: FR 1295304 (1962 to Equilibre Biologique), C.A. 58, 1536f (1963). Prepn of D,L isomers and racemate: FR 2115060 (1972 to Metabio), C.A. 78, 75877k (1972). Comparison with aspirin: S. Rampon et al., Rhumatologie 24, 141 (1972). Pharmacokinetics: H. von Ross et al., Klin. Wochenschr. 56, 1119 (1978); F. Gentit, Gaz. Med. Fr. 86, 4539 (1979). Veterinary use as analgesic: P. Richez et al., J. Vet. Pharmacol. Ther. 2, 231 (1979); eidem, ibid. 3, 121 (1980). Analgesic activity in post-operative pain: K. Korttila et al., Br. J. Anaesth. 52, 613 (1980); in articular pain: C. Diaz et al., Clin. Ther. 4, 121 (1981). Use in treatment of premature labor: F. Wolff et al., Arch. Gynecol. 233, 15 (1982). Comparison with aspirin in production of gastromucosal damage: J.-F. Bretagne et al., Gastroenterol. Clin. Biol. 8, 28 (1984).
Properties: Crystals from ethanol, mp 154-156°. Sol in water; slightly sol in ethanol. Insol in methanol, acetone, ether.
Melting point: mp 154-156°
Therap-Cat: Analgesic; antipyretic; anti-inflammatory.
Therap-Cat-Vet: Analgesic; antipyretic; anti-inflammatory.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Salicylic Acid Derivatives; Antipyretic.

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