Structural Formula Vector Image
Title: Lobelanidine
CAS Registry Number: 552-72-7
CAS Name: [2a(R*),6a(S*)]-1-Methyl-a,-diphenyl-2,6-piperidinediethanol
Additional Names: a,-[(1-methyl-2,6-piperidinediyl)dimethylene]dibenzyl alcohol
Molecular Formula: C22H29NO2
Molecular Weight: 339.47
Percent Composition: C 77.84%, H 8.61%, N 4.13%, O 9.43%
Literature References: From herb of Lobelia inflata L., Lobeliaceae: Wieland et al., Ann. 444, 40 (1925). Synthesis: Wieland, Drishaus, ibid. 473, 102 (1929). Comprehensive review of H. Wieland's work on Lobelia alkaloids with complete references is given by Schöpf, Naturwissenschaften 30, 359 (1942).
Properties: Scales from alc, mp 150°. Distills unchanged in vacuo. Freely sol in benzene, chloroform, acetone; slighty sol in ether, petr ether; almost insol in water.
Melting point: mp 150°
Derivative Type: Hydrochloride
Molecular Formula: C22H29NO2.HCl
Molecular Weight: 375.93
Percent Composition: C 70.29%, H 8.04%, N 3.73%, O 8.51%, Cl 9.43%
Properties: Needles from alcohol, mp 135-138°.
Melting point: mp 135-138°
Derivative Type: Hydrobromide
Molecular Formula: C22H29NO2.HBr
Molecular Weight: 420.38
Percent Composition: C 62.86%, H 7.19%, N 3.33%, O 7.61%, Br 19.01%
Properties: Crystals, mp 189°.
Melting point: mp 189°
Status: This monograph has been retired and is no longer subject to revision or update.

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