Structural Formula Vector Image
Title: Ifenprodil
CAS Registry Number: 23210-56-2
CAS Name: a-(4-Hydroxyphenyl)-b-methyl-4-(phenylmethyl)-1-piperidineethanol
Additional Names: 4-benzyl-a-(p-hydroxyphenyl)-b-methyl-1-piperidineethanol; 2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol; 1-methyl-2-hydroxy-2-(4-hydroxyphenyl)ethyl-1-(4-benzylpiperidine)
Manufacturers' Codes: RC-61-91
Molecular Formula: C21H27NO2
Molecular Weight: 325.44
Percent Composition: C 77.50%, H 8.36%, N 4.30%, O 9.83%
Literature References: Prepn and pharmacology: M. Carron et al., FR M5733; US 3509164 (1968, 1970 to Robert et Carrière); C. Carron et al., Arzneim.-Forsch. 21, 1992 (1971).
Properties: mp 114°.
Melting point: mp 114°
Derivative Type: Neutral tartrate
Trademarks: Cerocral (Funai); Dilvax (Promeco); Vadilex (Sanofi-Synthelabo)
Molecular Formula: (C21H27NO2)2.C4H6O6
Molecular Weight: 800.98
Percent Composition: C 68.98%, H 7.55%, N 3.50%, O 19.97%
Properties: Crystals from methanol, mp 178-180°. Sol in alc, water. Very slightly sol in acetone, chloroform. Practically insol in ether. LD50 in male Swiss mice (mg/kg): 17 i.v.; 120 i.p.; 275 orally (Carron, 1970).
Melting point: mp 178-180°
Toxicity data: LD50 in male Swiss mice (mg/kg): 17 i.v.; 120 i.p.; 275 orally (Carron, 1970)
Therap-Cat: Vasodilator (cerebral and peripheral).
Keywords: Vasodilator (Cerebral); Vasodilator (Peripheral).

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