Structural Formula Vector Image
Title: Fertilysin
CAS Registry Number: 1477-57-2
CAS Name: N,N¢-1,8-Octanediylbis[2,2-dichloroacetamide]
Additional Names: N,N¢-octamethylenebis(2,2-dichloroacetamide); N,N¢-bis(dichloroacetyl)-1,8-octamethylenediamine
Manufacturers' Codes: Win-18446
Molecular Formula: C12H20Cl4N2O2
Molecular Weight: 366.11
Percent Composition: C 39.37%, H 5.51%, Cl 38.73%, N 7.65%, O 8.74%
Line Formula: Cl2CHCONH(CH2)8NHOCCHCl2
Literature References: Inhibits spermatogenesis without affecting production of gonadotropins in male laboratory animals. Prepn and biological activity: Surrey, Mayer, J. Med. Pharm. Chem. 3, 419 (1961); Surrey, US 3143566 (1964 to Sterling Drug). Assessment of antifertility activity in rats: S. Nag, J. J. Ghosh, J. Steroid Biochem. 11(1B), 681 (1979). Teratological study: P. Taleporos et al., Teratology 18, 5 (1978). Toxicology study: F. Coulston et al., Toxicol. Appl. Pharmacol. 2, 715 (1960).
Properties: Crystals, mp 122.4-123.6°. LD50 orally in mice: >16000 mg/kg (Coulston).
Melting point: mp 122.4-123.6°
Toxicity data: LD50 orally in mice: >16000 mg/kg (Coulston)

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