Structural Formula Vector Image
Title: Fenbutrazate
CAS Registry Number: 4378-36-3
CAS Name: a-Ethylbenzeneacetic acid 2-(3-methyl-2-phenyl-4-morpholinyl)ethyl ester
Additional Names: 2-phenylbutyric acid 2-(3-methyl-2-phenylmorpholino)ethyl ester; 2-(3-methyl-2-phenylmorpholino)ethyl 2-phenylbutyrate; phenbutrazate
Molecular Formula: C23H29NO3
Molecular Weight: 367.48
Percent Composition: C 75.17%, H 7.95%, N 3.81%, O 13.06%
Literature References: Prepn: H. Siemer, O. Hengen, US 3018222 (1962 to Ravensberg). Physical properties and pharmacology: O. Hengen, H. Siemer, Arzneim.-Forsch. 5, 526 (1955).
Properties: Honey colored, viscous oil, bp0.05 235-240°. Sol in methanol with neutral reaction.
Boiling point: bp0.05 235-240°
Derivative Type: Hydrochloride
CAS Registry Number: 6474-85-7
Manufacturers' Codes: R-381
Molecular Formula: C23H29NO3.HCl
Molecular Weight: 403.94
Percent Composition: C 68.39%, H 7.49%, N 3.47%, O 11.88%, Cl 8.78%
Properties: Crystals, mp 154°. Slightly sol in water; sol in ethanol, acetone. Practically insol in ether, benzene. LD50 in mice (mg/kg): 3200 orally; 2800 s.c. (Hengen, Seimer).
Melting point: mp 154°
Toxicity data: LD50 in mice (mg/kg): 3200 orally; 2800 s.c. (Hengen, Seimer)
Derivative Type: Hydrochloride mixture with phenmetrazine theoclate
CAS Registry Number: 8004-38-4
Trademarks: Cafilon (Ravensberg); Filon (Berk)
Therap-Cat: Anorexic.
Keywords: Anorexic.

Other Monographs:
PyriminilTechnetium 99mTc Mertiatidep-XenylcarbimideCosyntropin
Tolciclatep-AminophenolSintropium BromideD-Ribulose
PropiverineTuaminoheptanePirifibrateSilver Chromate(VI)
Metoclopramide2-Azetidinecarboxylic AcidRhenium TrioxideCorycavamine
©2006-2023 DrugFuture->Chemical Index Database