Structural Formula Vector Image
Title: Famoxadone
CAS Registry Number: 131807-57-3
CAS Name: 5-Methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-2,4-oxazolidinedione
Additional Names: 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
Manufacturers' Codes: DPX-JE874
Trademarks: Famoxate (DuPont)
Molecular Formula: C22H18N2O4
Molecular Weight: 374.39
Percent Composition: C 70.58%, H 4.85%, N 7.48%, O 17.09%
Literature References: Inhibits electron transport via blockage of ubiquinol:cytochrome c oxidoreductase. Prepd not claimed: D. Geffken, D. R. Rayner, US 4957933 (1990 to DuPont). Biological activity and field trials: M. M. Joshi, J. A. Sternberg, Proc. Br. Crop Prot. Conf. - Pests Dis. 1996, 21. Mode of action: D. B. Jordan et al., Pestic. Sci. 55, 105 (1999). Environmental fate: K. M. Jernberg, P. W. Lee, ibid. 587. Metabolic fate in plants and animals: P. W. Lee et al., ibid. 589. Review of synthesis and structure-activity relationship: J. A. Sternberg et al., ACS Symp. Ser. 686, 216-227 (1998).
Properties: mp 140.3-141.8°. Log P (n-octanol/water): 4.65 (pH 7). Soly in water: 52 mg/L. LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Joshi, Sternberg).
Melting point: mp 140.3-141.8°
Log P: Log P (n-octanol/water): 4.65 (pH 7)
Toxicity data: LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Joshi, Sternberg)
Use: Agricultural fungicide.

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