Structural Formula Vector Image
Title: Etofylline
CAS Registry Number: 519-37-9
CAS Name: 3,7-Dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-1H-purine-2,6-dione
Additional Names: 7-(2-hydroxyethyl)theophylline; oxyethyltheophylline
Trademarks: Oxytheonyl; Oxphylline (Amido); Phyllocormin N
Molecular Formula: C9H12N4O3
Molecular Weight: 224.22
Percent Composition: C 48.21%, H 5.39%, N 24.99%, O 21.41%
Literature References: Obtained by the action of glycol monochlorohydrin upon theophylline in an alkaline medium: Lespagnol et al., Bull. Soc. Pharm. Lille 1948, no. 2, p 18; Roth, Arch. Pharm. 292, 234 (1959); Fabbrini, Cencioni, Farmaco Ed. Sci. 17, 660 (1962).
Properties: Crystals from abs ethanol, mp 158°. Freely sol in water. Moderately sol in alcohol. pH of a 5% aq soln 6.5-7.0. Solns may be sterilized by heating. Pharmacological action as of theophylline.
Melting point: mp 158°
Therap-Cat: Bronchodilator.
Keywords: Bronchodilator; Xanthine Derivatives.

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